Bone marrow CXCR4 induction by cultivation enhances therapeutic angiogenesis
نویسندگان
چکیده
منابع مشابه
Bone marrow CXCR4 induction by cultivation enhances therapeutic angiogenesis.
AIMS The chemokine stromal cell-derived factor-1 (SDF-1) and its receptor (CXCR4, CXC chemokine receptor 4) play a critical role in the process of post-natal neovascularization. Here, we investigated the role of CXCR4(+) bone marrow cells (BMCs) in neovascularization in a murine hindlimb ischaemia model. METHODS AND RESULTS We found that the expression of CXCR4 in BMCs was specifically upregu...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2008
ISSN: 1755-3245,0008-6363
DOI: 10.1093/cvr/cvn247